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Leucovorin (Folinic Acid) and Autism: New Hope for Improving Speech in Children Autism Spectrum Disorder (ASD) often comes with profound challenges in speech and communication

Their activation and incorporation into phospholipids are orchestrated by acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), two critical regulators of ferroptosis (Dixon et al., 2015

Finally, in both the absence and presence of IL-1, PPAR was significantly induced by GS at 1 and 2 mM (p 0.03)

The search cutoff was August 2025, corresponding to the manuscript submission date, to ensure inclusion of the most up-to-date available evidence